Mind your wellness Normal Immune System1 Increased maternal folate status2 1Folic Acid contributes to the normal function of the immune system. 2Supplemental folic acid intake increases maternal folate status. Low maternal folate status is a risk factor in the development of neural tube defects in the developing fetus. The target population is women of childbearing age, and the beneficial effect is obtained with a supplemental folic acid intake of 400 µg for at least one month before and up to t